DRAGEN Solid WGS Tumor Normal Pipeline
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DRAGEN Solid WGS Tumor Normal Pipeline, henceforth referred as the Solid WGS TN Pipeline, is a comprehensive and unbiased whole genome sequencing solution for detection of all types of mutation in matched tumor and normal samples. It can be applied to detect clinically actionable mutations for cancer spanning a wide range of genomic events, e.g., structural variants (SV), Copy Number Alterations (CNA), small variants (SNV/insertion/deletion/delins).
The Solid WGS TN pipeline includes a DNA-only workflow designed to analyze whole genome sequencing data generated on supported instruments. It may be run as a local off-instrument solution installable on a DRAGEN server or accessible through the Illumina Connected Analytics (ICA) cloud environment. The Solid WGS TN pipeline is for Research Use Only (RUO).
Superb performance based on the DRAGEN BioIT platform Release 4.4.4
Supports starting the analysis from FASTQ (.gz or .ora format), BAM or CRAM as inputs
Flexible custom configurable options on top of well established DRAGEN recipes for Solid WGS TN analysis.
Available on local DRAGEN servers and Illumina Connected Analytics (ICA)
Seamless integration with Illumina Connected Insights (ICI) for tertiary interpretation
No specific requirements on LPKs since the pipeline does not support starting from BCL in the curent release.
No specific requirements on instruments since the pipeline does not support starting from BCL in the curent release.
